The subsequent adverse reactions are already determined throughout submit approval usage of oxycodone and acetaminophen tablets.

The oxycodone in oxycodone and acetaminophen tablets may perhaps enhance the frequency of seizures in sufferers with seizure Conditions, and may increase the danger of seizures transpiring in other clinical configurations associated with seizures.

Adrenal insufficiency: Circumstances of adrenal insufficiency happen to be reported with opioid use, more frequently adhering to higher than a person thirty day period of use.

Clients must be educated concerning the indications of great skin reactions, and use from the drug needs to be discontinued at the main look of skin rash or some other indicator of hypersensitivity.

The developmental and health great things about breastfeeding ought to be deemed combined with the mother's clinical will need for oxycodone and acetaminophen tablets and any potential adverse consequences to the breastfed toddler from oxycodone and acetaminophen tablets or from your fundamental maternal issue.

Reserve concomitant prescribing of these medicine for use in clients for whom choice treatment method possibilities are inadequate. Restrict dosages and durations towards the least demanded.

Go through the Medication Guide supplied by your pharmacist before you start taking oxycodone/acetaminophen and every time you have a refill. When you've got any issues, question your medical doctor or pharmacist.

Absorption of acetaminophen is quick and Pretty much full through the GI tract following oral administration. With overdosage, absorption is comprehensive in four hours.

Zidovudine The pharmacologic effects of zidovudine can be lowered due to enhanced non-hepatic or renal clearance of zidovudine.

Notify woman individuals of reproductive potential that oxycodone and acetaminophen tablets can result in fetal damage and to tell the healthcare supplier of a regarded or suspected pregnancy [see Safeguards; PREGNANCY].

To inform family and friends about their naloxone and to keep it in a location exactly where friends and family can entry it within an emergency

To scale back the potential risk of dizziness and lightheadedness, rise up little by little when increasing from the sitting or lying posture.

As a result of comparable pharmacological Qualities, it is actually acceptable to anticipate very similar chance Using the concomitant use of other CNS depressant medications with opioid more info analgesics [see PRECAUTIONS; Drug Interactions].

Carbon dioxide (CO2) retention from opioid-induced respiratory despair can exacerbate the sedating effects of opioids. When significant, lifestyle-threatening, or deadly respiratory depression can come about Anytime all through using PERCOCET, the chance is greatest in the initiation of therapy or subsequent a dosage raise.